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How Charred Meat Could Raise Cancer Risk & What Steps to Take

Introduction

Cooking meat on an open flame is a favorite tradition globally. However, different studies highlight that cooking meat at extreme or high temperatures till it becomes charred can increase the risk of developing cancer. This blog will discuss how charred meat increases cancer risk and what measures you can take to minimize these life-threatening risks.

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Cancer

Charred Meat

Cancer ranks as the primary cause of death worldwide, affecting millions of people. This disease involves a group of diseases categorized by abnormal growth and spread of abnormal cells.IN 2020, WHO and IARC reported around 19.3 million new cases of cancer and 10 million mortalities due to cancer globally in 2020. Additionally, the most common types of cancer are breast, colorectal, prostate, stomach, and lung. Cancer prevalence differs geographically. Certain risk factors are associated with cancer such as age, gender, environmental factors, certain lifestyle, etc.

Charred Meat and Cancer

Preparing meat at high temperatures can produce carcinogenic chemicals. Charred meat health risks is due to the formation of carcinogenic chemicals. Moreover, cooking meat at high temperatures produces two main types of harmful chemicals that are as follows:

Heterocyclic Amines

When amino acids, creatine, and sugar react at high temperatures it produces heterocyclic amines (HCAs). Different studies indicate that these chemicals can alter DNA, thus resulting in the development of cancerous cells, additionally, HCAs form at temperatures above 300⁰F.

Polycyclic Aromatic Hydrocarbons

When fat and liquid/juices from meat drips on the open flame, it causes smoke, thus producing polycyclic aromatic hydrocarbons (PAHs). The smoke has PAHs which stick to the meat surface.

Studies show the association between an increased intake of charred meat and increased cancer risk such as colorectal, and prostate cancer, etc. However, different ongoing researchers trying to study the exact mechanisms.

Studies on the Association between Charred Meat and Different Types of Cancer

Let’s discuss the research on the association between charred meat and cancer. Different studies show the charred meat cancer risk.

Colorectal Cancer

Colorectal cancer is the third most prevalent cancer type globally. Numerous researches highlight that charred meat increases colorectal cancer risk. One study concluded that individuals who regularly eat charred meat have a 30-40% higher risk of colorectal cancer than those who consume less charred meat. Furthermore, studies show that HCAS and PAHs form during high heat cause mutations in the colon thus promoting the production of cancerous cells.

Pancreatic Cancer

This is one of the most life-threatening cancer types because of its difficulty in early diagnosis and aggressive nature. Recent research shows the association between charred meat and pancreatic cancer. For instance, one research concluded that individuals consuming charred meat had a two-fold higher risk of developing pancreatic cancer than those who eat/consume less charred meat. Furthermore, studies concluded that carcinogenic chemicals formed while preparing charred meat might affect the pancreas.

Prostate Cancer

Studies show the association between charred meat and prostate cancer. Moreover, prostate cancer is the second most prevalent cancer type among men. For instance, one study concluded that men who eat high amounts of charred meat had 50% higher prostate cancer risk than those consuming charred meat in low amounts. Furthermore, different studies found that the carcinogenic chemicals formed while cooking meat at high temperatures lead to DNA mutations, thus causing prostate cancer.

The Effect of HCAs and PAHs on DNA

HCAs and PAHs can cause DNA damage by different mechanisms. They both can directly bind to DNA and form DNA adducts. Moreover, this process happens when the electrophilic region of these chemicals reacts with the nucleophilic region on DNA bases, causing structural alterations. Furthermore, DNA adducts can interfere with the process of DNA replication and transcription causing mutations.

Another way by which these chemicals can cause DNA damage is oxidative stress. These two chemicals can produce reactive oxygen species. The increased level of reactive oxygen species causes oxidative changes to DNA bases resulting in base oxidation and strand breakage.

Furthermore, oxidative stress and DNA adduct formation can put pressure on the DNA repair mechanism. When the repair mechanism doesn’t work properly, the resulting mutations can build up, increasing the possibility of cancerous transformations.

Thus, DNA damage can contribute to the development of cancer. The mutations may lead to oncogenes activation or inactivation of tumor suppressor genes. Moreover, DNA damage may promote processes like angiogenesis and inflammation that support the development of tumors.

Steps to Reduce the Risk of Cancer due to Charred Meat

Here are some ways of reducing cancer risk from charred meat.

  • One of the easiest ways to reduce HCAs and PAHs formation is by preparing charred meat at low temperatures. Cooking at high temperatures results in the formation of these chemicals so using techniques like stewing, baking, etc. can decrease the level of these carcinogenic chemicals in the food.
  • Pre-cooking the meat in the microwave or oven can reduce the time period the meat spends at high temperatures. Thus, this technique helps you to enjoy the flavors of charred meat without preparing them directly on the flame for a longer period.
  • Marination before frying or grilling can reduce HCA formation. Moreover, the acidic marinades can reduce the formation of HCA. The antioxidants in acidic marinades neutralize the harmful chemicals before they can form.
  • Polycyclic aromatic hydrocarbons form when fat drips on the flames, this produces smoke that contaminates the meat. One technique to avoid this is to choose slim cuts of meat. Another way is to place the meat on foil to avoid dripping fat. Moreover, using a drip pan may minimize the PAH exposure.
  • Incorporate vegetables into meat, as vegetables don’t produce the HCAs and PAHs when cooked. Moreover, vegetables contain antioxidants that protect against DNA damage.
  • Flipping meat frequently while preparing may reduce the production of HCAs as it reduces the period the meat is in direct contact with high temperatures.
Charred Meat

Changes in Lifestyle to Reduce Cancer Risk

Adopting a healthy lifestyle is crucial for reducing cancer risk. Some strategies are as follows:

  • Incorporating plant-based foods into the diet is a way to reduce cancer risk. Moreover, reducing the overall intake of processed and red meat lowers the risk of colorectal cancer and other types of cancer.
  • Processed meat increases the risk of cancer. The WHO categorizes processed meats as Group 1 carcinogens, implying there is strong proof that they cause cancer. Thus, limiting the intake of processed meat can reduce cancer risk.
  • Do regular physical activities, this lowers the cancer risk. Moreover, physical exercises reduce inflammation and improve the function of the immune system.
  • Being obese poses a risk for various types of cancer. Thus, weight management by eating a well-balanced diet and engaging in physical exercises helps lower cancer risk.

Conclusion

In conclusion, while many people enjoy consuming charred meat, it’s crucial to be aware of the cancer risk posed by heterocyclic amines and polycyclic aromatic hydrocarbons. By recognizing how these carcinogenic chemicals form and taking measures to reduce their production, an individual can enjoy charred meat while having low cancer risk. Preparing your meat at low temperatures, using acidic marinades, and including plant-based foods in your diet are some of the effective strategies for lowering the cancer risk. Furthermore, little changes in cooking habits can improve overall well-being while still allowing an individual to enjoy the flavors they love.

FAQ

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Charred meat is prepared by cooking at high temperatures, often over a grill or an open flame, till the surface becomes burnt. This procedure can produce harmful chemicals like HCAs and PAHs.

Yes, consuming charred meat poses a risk of several types of cancer because of the formation of certain carcinogenic chemicals while preparing it. 

Charred meat can cause cancer because of the production of harmful chemicals when an individual cooks the meat at high temperatures or on an open flame. These chemicals can cause damage to DNA and can lead to mutations or alterations, thus increasing the risk of cancer.

Charred meat produces two main types of harmful chemicals heterocyclic amines and polycyclic aromatic hydrocarbons. They are carcinogenic and can cause various types of cancer.

Yes, different studies confirmed the association between charred meat and cancer. Moreover, different studies show the association of charred meat with colorectal cancer, prostate cancer, breast cancer, pancreatic cancer, and other types of cancer.

Some mindful strategies can minimize the risk. Frequently flip the meat, pré-cook the meat in the microwave or oven, incorporate vegetables, use acidic marinades, etc. These strategies will be effective in lowering the cancer risk.

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